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. 2014 Sep 5;9(9):e107058. doi: 10.1371/journal.pone.0107058

Figure 5. Effects of naringenin (NGEN) or naringenin complexed with copper (II) and 2,2′-bipyridine (NGENCuB) on MDA-MB-231 cell migration.

Figure 5

A. Cells were scratched using a pipette tip to make gaps between cells before NGEN and NGENCuB treatment. At 0, 6, 12, 24 and 48 hours of treatment, the plates were photographed under a light microscope (40 x). B. Percentage of wound closure of control cells or cells treated with 100 µM of NGEN or NGENCuB. Results are expressed as percent of wound closure relative to control (untreated) cells. Data represent mean ± SD of three independent assays in triplicate. Results were compared using ANOVA, followed by a Tukey's post-hoc analysis. Asterisks represent *p≤0.05, **p≤0.01, ***p≤0.001 compared to control.