Figure 3.

Predicted miRNA targets. (A) Potential base pairing between predicted MREs derived from the indicated mRNAs (black) and their cognate miRNAs (blue). Numbers refer to nucleotide positions after the stop codon, based on the human mRNAs. (B) HeLa (blue bars) or MN-1 (orange bars) cells were cotransfected with Renilla luciferase (RL) constructs bearing the indicated MREs in the 3′-UTR, along with firefly luciferase (FL). Results shown are average values (with standard deviations) of normalized RL/FL activities obtained from six separate experiments.