Figure 2. Expression of nuclear hnRNPA2 protein is upregulated in high-grade PCa. (A) Nuclear hnRNPA2 protein expression in clinical prostate samples. Representative images from hnRNPA2-immunostained sections for BPH (left panel), Gleason grades 3 (middle panel) and 5 (right panel). (Bar = 100 µm). (B) Histoscore populations are graphically represented using a box and whisker plot, as these data are not normally distributed. Statistical analysis revealed significant overexpression of nuclear hnRNPA2 protein in Gleason 4 and 5 PCa as compared with BPH controls (P = 0.03).