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Effect of MAPK inhibitors on H. pylori-induced Egr-1 expression. AGS cells were preincubated for 30 min with the MEK1/2 MAPK inhibitors PD98059 (20 μM) and U0126 (10 μM) and the specific p38 MAPK inhibitor SB 203580 (10 μM) and were then cocultured with H. pylori (6 × 108 CFU/ml) for 2 h.
