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. Author manuscript; available in PMC: 2015 Sep 2.
Published in final edited form as: Cell Metab. 2014 Jul 17;20(3):512–525. doi: 10.1016/j.cmet.2014.06.010

Figure 4. Hepatic JNK-deficiency increases peroxisome number and mitochondrial size.

Figure 4

(A, B) LWT and LΔ1,2 mice were fed a HFD (16 wks). Sections of the liver were examined by transmission electron microscopy. Representative images are presented. Key: nucleus (N); lipid droplet (LD). Arrow heads indicate peroxisomes (A) and mitochondria (B). Bar, 2 μm (A) and 0.5 μm (B).

(C, D) The number of peroxisomes (C) and mitochondria (D) per field was measured (mean ± SEM; n = 30; *, p < 0.05).

(E) Relative mitochondrial DNA copy number was measured (mean ± SEM; n = 3).