Table 1. Demographic and clinical characteristics of a U.S. chronic HCV population in a commercial insurance database, 2006-2010.
| 2006 | 2007 | 2008 | 2009 | 2010 | Weighted Average | |
|---|---|---|---|---|---|---|
| Enrollees, n | (71,584 individuals, 106,283 cross-sections) | |||||
| 16,216 | 16,235 | 25,380 | 24,683 | 23,769 | N=106,283 | |
|
| ||||||
| Sociodemographics, % | ||||||
|
| ||||||
| Age in years, mean | 49.7 | 50.4 | 51.2 | 51.8 | 52.4 | 51.2 |
| (±SD) | (7.3) | (7.3) | (7.5) | (7.5) | (7.6) | (7.5) |
| Gender, male | 61.5 | 61.4 | 62.1 | 62.6 | 62.8 | 62.2 |
|
| ||||||
| Health plan type | ||||||
| Comprehensive | 4.9 | 2.0 | 2.7 | 2.3 | 2.8 | 2.9 |
| HMO | 14.7 | 15.1 | 23.1 | 18.5 | 16.7 | 18.1 |
| POS | 10.6 | 11.0 | 9.3 | 8.4 | 8.0 | 9.3 |
| PPO | 67.3 | 69.4 | 62.1 | 67.7 | 64.0 | 65.7 |
|
| ||||||
| Region | ||||||
| Northeast | 8.8 | 7.5 | 18.6 | 12.5 | 16.2 | 13.5 |
| North Central | 19.8 | 18.7 | 15.5 | 16.3 | 15.6 | 16.8 |
| South | 51.5 | 52.5 | 48.1 | 50.6 | 42.6 | 48.6 |
| West | 19.5 | 20.9 | 17.6 | 20.5 | 24.8 | 20.7 |
|
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| Comorbidities, % | ||||||
|
| ||||||
| Metabolic | ||||||
| Hypertension | 32.0 | 34.8 | 37.5 | 43.2 | 44.7 | 39.2 |
| Lipid metabolism disorders | 19.2 | 20.8 | 22.4 | 26.7 | 27.5 | 23.8 |
| Type II diabetes | 16.4 | 17.3 | 18.7 | 20.0 | 20.3 | 18.8 |
| Clinically-defined obesity | 2.1 | 2.8 | 3.2 | 5.9 | 6.5 | 4.3 |
|
| ||||||
| Psychiatric | ||||||
| Depression | 12.2 | 13.0 | 12.6 | 16.2 | 16.7 | 14.4 |
| Drug abuse/dependence | 3.3 | 3.1 | 3.7 | 5.3 | 5.6 | 4.3 |
| Alcohol abuse/dependence | 2.9 | 3.1 | 3.8 | 5.3 | 5.8 | 4.3 |
| Bipolar disorders | 2.2 | 2.4 | 2.5 | 2.9 | 2.9 | 2.6 |
|
| ||||||
| Hepatic | ||||||
| Compensated cirrhosis | 18.0 | 19.9 | 20.2 | 23.6 | 26.5 | 22.0 |
| Advanced liver disease | 9.9 | 10.7 | 11.1 | 13.8 | 15.5 | 12.5 |
| NAFLD | 5.0 | 5.7 | 6.5 | 8.1 | 8.8 | 7.0 |
| Alcoholic liver disease | 3.9 | 4.0 | 4.2 | 5.0 | 5.9 | 4.7 |
| Liver transplant | 3.2 | 3.4 | 3.7 | 4.3 | 4.7 | 3.9 |
| Viral hepatitis B | 3.6 | 3.5 | 4.0 | 3.5 | 3.6 | 3.7 |
| Hepatocellular carcinoma | 1.8 | 2.3 | 3.1 | 3.3 | 4.0 | 3.0 |
|
| ||||||
| Other | ||||||
| COPD or asthma | 8.0 | 8.8 | 9.4 | 11.1 | 11.6 | 10.0 |
| Rheumatoid arthritis | 3.1 | 3.0 | 3.1 | 3.4 | 3.4 | 3.2 |
| HIV/AIDS | 1.9 | 2.2 | 3.0 | 3.2 | 3.2 | 2.8 |
Abbreviations: SD, standard deviation; chronic HCV, chronic Hepatitis C virus infection; HMO, Health Maintenance Organization; POS, Point of Service; PPO, Preferred Provider Organization; NAFLD: non-alcoholic fatty liver disease; COPD, chronic obstructive pulmonary disease; HIV/AIDS: human immunodeficiency virus/acquired immunodeficiency syndrome