Table 5.
Antitubercular activities of lead benzimidazoles against drug-sensitive and multidrug-resistant Mtb strains
| Compound | MIC99 (µg/mL) Mtb strains |
|||
|---|---|---|---|---|
| H37Rv | NHN382 | TN587 | W210 | |
| SB-P3G2 | 0.63 | 1.25 | 1.25 | 1.25 |
| SB-P8B2 | 0.39 | 0.31 | 0.16 | 0.63 |
| SB-P17G-C2 | 0.06 | 0.06 | 0.13 | 0.06 |
| SB-P20G3 | 0.16 | 0.16 | 0.16 | 0.16 |
| SB-P17G-A20 | 0.16 | 0.16 | 0.16 | 0.16 |