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. 2014 Aug 20;15:98. doi: 10.1186/1471-2202-15-98

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© Boaru et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Bioimaging of sodium and phosphate in the murine brain. Thin brain section of WT (upper panel) and Atp7b deficient mice (lower panel) were prepared by cryo-cutting and analyzed for Na and P content by LA-ICP-MS. In these measurements, the metal intensities were normalized to the average ¹³C ion intensity in respective samples. The photomicrographs of the analyzed cryo-sections are depicted for orientation.