FIG. 2.

Disorganization of muscle fiber cytoskeleton observed 1 day after mice received a sublethal intramuscular injection of C. sordellii LT. Single-teased fibers from control TA muscles (panels A and C) and from LT-injected muscles (panels B and D) were immunostained with anti-α-actinin (panels A and B) and anti-troponin T (panels C and D) antibodies. Note the striated and regular parallel lines of the two immunostained muscle proteins in the control muscles (panels A and C) and the loss of the striated appearance associated with a disoriented meshwork of myofilaments in LT-injected muscles (panels B and D). Bar = 20 μm.