Table 3.
Clinicopathologic features | Intratumoral EpCAM density | PValue | Intratumoral OV6 density | PValue | Intratumoral CD133 density | PValue | Intratumoral c-kit density | P Value | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
High | Low | High | Low | High | Low | High | Low | |||||
Frequency (%) | 39 (32.5%) | 81 (67.5%) | 26 (21.7%) | 94 (78.3%) | 29 (24.2%) | 91 (75.8%) | 34 (28.3%) | 86 (71.7%) | ||||
Gender | ||||||||||||
Male | 34 | 74 | 0.697 | 21 | 87 | 0.161 | 26 | 82 | 1.000 | 32 | 76 | 0.543 |
Female | 5 | 7 | 5 | 7 | 3 | 9 | 2 | 10 | ||||
Age | ||||||||||||
≤60 | 19 | 44 | 0.565 | 19 | 62 | 0.493 | 13 | 50 | 0.342 | 19 | 44 | 0.641 |
>60 | 20 | 37 | 7 | 32 | 16 | 41 | 15 | 42 | ||||
AFP | ||||||||||||
≤400 | 17 | 64 | <0.001* | 19 | 62 | 0.493 | 20 | 61 | 0.847 | 23 | 58 | 0.983 |
>400 | 22 | 17 | 7 | 32 | 9 | 30 | 11 | 28 | ||||
Cirrhosis | ||||||||||||
Absence | 21 | 50 | 0.411 | 10 | 61 | 0.015* | 14 | 57 | 0.171 | 17 | 54 | 0.199 |
Presence | 18 | 31 | 16 | 33 | 15 | 34 | 17 | 32 | ||||
Satellite lesion | ||||||||||||
Absence | 33 | 72 | 0.507 | 22 | 83 | 0.867 | 27 | 78 | 0.468 | 33 | 72 | 0.092 |
Presence | 6 | 9 | 4 | 11 | 2 | 13 | 1 | 14 | ||||
Tumor size (cm) | ||||||||||||
≤5cm | 15 | 37 | 0.455 | 14 | 38 | 0.222 | 13 | 39 | 0.852 | 12 | 40 | 0.264 |
>5cm | 24 | 44 | 12 | 56 | 16 | 52 | 22 | 46 | ||||
Tumor encapsulation | ||||||||||||
Absence | 26 | 61 | 0.321 | 18 | 69 | 0.673 | 19 | 68 | 0.334 | 27 | 60 | 0.286 |
Presence | 13 | 20 | 8 | 25 | 10 | 23 | 7 | 26 | ||||
Microvascular invasion | ||||||||||||
Absence | 15 | 40 | 0.261 | 14 | 41 | 0.354 | 12 | 43 | 0.580 | 17 | 38 | 0.565 |
Presence | 24 | 41 | 12 | 53 | 17 | 48 | 17 | 48 | ||||
Major vascular invasion | ||||||||||||
Absence | 34 | 80 | 0.023* | 25 | 89 | 1.000 | 28 | 86 | 1.000 | 32 | 82 | 1.000 |
Presence | 5 | 1 | 1 | 5 | 1 | 5 | 2 | 4 | ||||
Edmondson grade | ||||||||||||
Low (I/II) | 23 | 67 | 0.005* | 17 | 73 | 0.201 | 19 | 71 | 0.176 | 20 | 70 | 0.010* |
High (III/IV) | 16 | 14 | 9 | 21 | 10 | 20 | 14 | 16 | ||||
TNM stage | ||||||||||||
I/II | 27 | 65 | 0.181 | 17 | 75 | 0.124 | 20 | 72 | 0.260 | 28 | 64 | 0.354 |
III | 12 | 16 | 9 | 19 | 9 | 19 | 6 | 22 |
*p <0 .05 was considered statistically significant.