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3D architecture of the nucleus. (a) Volume-rendered 3D image of a whole, unstained nucleus. (b) Nuclear substructures of chromatin region (blue), nucleolus (∼330 nm in red), condensed chromatin (∼340 nm in green), and nuclear bodies or speckles (∼80 nm in cyan). (c and d) Side and top views of the nucleus are shown. To visualize the nuclear substructures clearly, the nuclear envelope is not displayed. To see this figure in color, go online.
