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. 2014 Aug 7;136(35):12469–12478. doi: 10.1021/ja507166g

Table 4. Cross Metathesis of Amino Acids 3 and 5a.

graphic file with name ja-2014-07166g_0008.jpg

      yielda (%)
Z selectivityb (%)
entry equiv of 3 equiv of 5a 1 2 1 2
1 1 1 41 47 90 93
2 1 2 44 48 86 91
3 1 4 48 41 91 90
4 1 6 58 60 88 90
5 2 1 44 58 90 93
6 4 1 52 57 91 91
7 6 1 51 60 87 90
a

Isolated yields.

b

Determined by 1H or 13C NMR spectroscopy.