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. 2014 Aug 7;136(35):12469–12478. doi: 10.1021/ja507166g

Table 5. Cross Metathesis of Amino Acids 3 and 5s.

graphic file with name ja-2014-07166g_0009.jpg

      yielda (%)
Z selectivityb (%)
entry equiv of 3 equiv of 5s 1 2 1 2
1 1 1 46 47 90 93
2 1 2 43 48 84 90
3 1 4 38 41 84 91
4 1 6 34 38 72 88
5 2 1 47 58 88 91
6 4 1 58 60 90 92
7 6 1 62 66 87 90
a

Isolated yields.

b

Determined by 1H or 13C NMR spectroscopy.