Table 1.
Baseline characteristics of participants: The ARIC Study.
| Cancer-free N=11,634 | Cancer
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|---|---|---|---|---|---|---|---|---|---|
| Lung N=400 | p* | Breast N=522 | p* | Prostate N=615 | p* | Colorectal N=303 | p* | ||
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| Baseline SRH, mean (sd) | 74.9 (24.4) | 68.4 (26.5) | <0.0001 | 75.6 (23.9) | 0.5 | 75.3 (23.9) | 0.7 | 72.4 (25.5) | 0.08 |
| Excellent, n (%) | 3,978 (34.2) | 85 (21.3) | 177 (33.9) | 212 (34.5) | 90 (29.7) | ||||
| Good, n (%) | 5,378 (46.3) | 202 (50.5) | 252 (48.3) | 285 (46.3) | 143 (47.2) | ||||
| Fair, n (%) | 1,886 (16.2) | 94 (23.5) | 73 (14.0) | 106 (17.2) | 59 (19.5) | ||||
| Poor, n (%) | 386 (3.3) | 19 (4.7) | <0.0001 | 20 (3.8) | 0.5 | 12 (2.0) | 0.3 | 11 (3.6) | 0.3 |
| Age, mean (sd) | 53.7 (5.7) | 56.8 (5.5) | <0.0001 | 54.6 (5.8) | 0.0004 | 56.3 (5.6) | <0.0001 | 55.6 (5.5) | <0.0001 |
| Gender, n (%) | |||||||||
| Male | 5,050 (43.4) | 263 (65.7) | 0 (0.0) | 615 (100.0) | 157 (51.8) | ||||
| Female | 6,584 (56.6) | 137 (34.3) | <0.0001 | 522 (100.0) | <0.0001 | 0 (0.0) | <0.0001 | 146 (48.2) | 0.004 |
| Race/Community, n (%) | |||||||||
| Black/NC | 374 (3.2) | 15 (3.8) | 16 (3.1) | 21 (3.4) | 5 (1.7) | ||||
| Black/MS | 2,914 (25.0) | 79 (19.7) | 109 (20.9) | 174 (28.3) | 82 (27.1) | ||||
| White/NC | 2,576 (22.1) | 104 (26.0) | 122 (23.4) | 127 (20.7) | 61 (20.1) | ||||
| White/MN | 2,865 (24.6) | 88 (22.0) | 140 (26.8) | 157 (25.5) | 68 (22.4) | ||||
| White/MD | 2,905 (25.0) | 114 (28.5) | 0.04 | 135 (25.9) | 0.3 | 136 (22.1) | 0.3 | 87 (28.7) | 0.2 |
| Body Mass Index, n (%) | |||||||||
| Underweight | 102 (0.9) | 6 (1.5) | 4 (0.8) | 1 (0.2) | 3 (1.0) | ||||
| Normal | 3,723 (32.1) | 171 (42.8) | 184 (35.5) | 159 (25.9) | 81 (26.7) | ||||
| Overweight | 4,547 (39.1) | 142 (35.5) | 166 (32.0) | 296 (48.2) | 115 (38.0) | ||||
| Obese | 3,243 (27.9) | 81 (20.2) | <0.0001 | 165 (31.8) | 0.01 | 158 (25.7) | <0.0001 | 104 (34.3) | 0.07 |
| Smoker, n (%) | |||||||||
| Current | 2,872 (24.7) | 270 (67.5) | 121 (23.2) | 126 (20.5) | 77 (25.4) | ||||
| Former | 3,731 (32.1) | 109 (27.3) | 118 (22.6) | 288 (46.8) | 96 (31.7) | ||||
| Never | 5,021 (43.2) | 21 (5.2) | <0.0001 | 283 (54.2) | <0.0001 | 201 (32.7) | <0.0001 | 130 (42.9) | 1 |
| Drinker, n (%) | |||||||||
| Current | 6,327 (54.7) | 254 (63.5) | 271 (52.1) | 371 (60.8) | 166 (55.1) | ||||
| Former | 2,188 (18.9) | 97 (24.3) | 74 (14.2) | 139 (22.8) | 59 (19.6) | ||||
| Never | 3,055 (26.4) | 49 (12.2) | <0.0001 | 175 (33.7) | 0.0003 | 100 (16.4) | <0.0001 | 76 (25.2) | 0.9 |
| Education, n (%) | |||||||||
| Less than HS | 2,756 (23.7) | 142 (35.5) | 121 (23.2) | 140 (22.8) | 81 (26.7) | ||||
| HS or equivalent | 3,749 (32.3) | 137 (34.3) | 179 (34.3) | 163 (26.5) | 97 (32.0) | ||||
| Greater than HS | 5,105 (44.0) | 121 (30.2) | <0.0001 | 222 (42.5) | 0.6 | 312 (50.7) | 0.002 | 125 (41.3) | 0.4 |
| Comorbidities, n (%) | |||||||||
| CVD | 1,100 (9.5) | 57 (14.3) | 0.001 | 43 (8.2) | 0.4 | 58 (9.4) | 1 | 29 (9.6) | 0.9 |
| Chronic Lung Disease | 1,002 (8.6) | 66 (16.5) | <0.0001 | 46 (8.8) | 0.9 | 45 (7.3) | 0.3 | 29 (9.6) | 0.6 |
| Hypertension | 4,009 (34.6) | 154 (38.7) | 0.09 | 190 (36.5) | 0.4 | 253 (41.4) | 0.0006 | 116 (38.3) | 0.2 |
| Diabetes | 907 (7.8) | 26 (6.5) | 0.3 | 35 (6.7) | 0.3 | 34 (5.5) | 0.04 | 35 (11.6) | 0.02 |
| High Cholesterol | 2,404 (21.2) | 86 (22.3) | 0.6 | 103 (20.4) | 0.6 | 121 (20.0) | 0.5 | 69 (23.2) | 0.4 |
| Access to Care, n (%) | |||||||||
| No Health Insurance | 1,155 (10.0) | 46 (11.5) | 0.3 | 51 (9.8) | 0.9 | 53 (8.6) | 0.3 | 43 (14.2) | 0.02 |
| Physical Activity Score, mean (sd) | 2.42 (0.80) | 2.36 (0.75) | 0.1 | 2.31 (0.75) | 0.002 | 2.57 (0.80) | <0.0001 | 2.46 (0.78) | 0.4 |
| Freq. of Routine Exams, n (%) | |||||||||
| ≥Yearly | 5,041 (43.4) | 150 (37.6) | 240 (46.2) | 223 (36.3) | 128 (42.4) | ||||
| ≥Every 5 year and <Yearly | 2,740 (23.6) | 93 (23.3) | 119 (22.9) | 180 (29.3) | 80 (26.5) | ||||
| <Every 5 years/No routine exams | 3,823 (32.9) | 156 (39.1) | 0.02 | 160 (30.8) | 0.4 | 211 (34.4) | 0.0005 | 94 (31.1) | 0.5 |
*
p-value comparing the cancer group to the cancer-free group.