FIG. 5.

Determination of the extent of meningococcal bacteremia in individual mice following injection of N. meningitidis tbpB isotype II strain M982 and its mutants defective in either or both Tbps. Bacteremia (CFU/milliliter) was determined in individual murine blood samples taken 3 (open bars) and 24 h (striped bars) after injection of each strain. The number of mice (n = 6) who survived was registered 48 h after injection, which is indicated at the bottom of the graph. The bars indicate the geometric average of the bacteremic results.