Table 5.
Baseline characteristics of the 9361 SPRINT participants, presented as N (%) or mean (SD).
| Characteristic | SPRINT N=9361 | Intensive (N=4678) | Standard (N=4683) |
|---|---|---|---|
| Gender (Female) | 3333 (35.6) | 1684 (36.0%) | 1649 (35.2%) |
| Age (years) | 67.9 (9.4) | 67.9 (9.4) | 67.9 (9.5) |
| Race/Ethnicity | |||
| Black | 2802 (29.9) | 1379 (29.5) | 1423 (30.4) |
| Hispanic | 984 (10.5) | 503 (10.8) | 481 (10.3) |
| White | 5399 (57.7) | 2698 (57.7) | 2701 (57.7) |
| Other | 176 (1.9) | 98 (2.1) | 78 (1.7) |
| Age ≥75 years | 2636 (28.2) | 1317 (28.2) | 1319 (28.2) |
| Age among ≥75 (years) | 79.8 (4.0) | 79.8 (3.9) | 79.9 (4.1) |
| Baseline blood pressure (mm Hg) | |||
| Systolic | 139.7 (15.6) | 139.7 (15.8) | 139.7 (15.4) |
| Diastolic | 78.1 (11.9) | 78.2 (11.9) | 78.0 (12.0) |
| Baseline chronic kidney disease (estimated glomerular filtration rate<60) | 2648 (28.3) | 1331 (28.4) | 1317 (28.1) |
| Serum creatinine (mg/dL) | 1.07 (0.34) | 1.07 (0.34) | 1.08 (0.34) |
| estimated glomerular filtration rate (mL/min/1.73 m2) | 71.8 (20.6) | 71.8 (20.7) | 71.7 (20.5) |
| estimated glomerular filtration rate<45 mL/min/1.73 m2 | 890 (9.5) | 446 (9.5) | 444 (9.5) |
| Urine albumin/creatinine (mg/g) | 42.6 (166.3) | 44.1 (178.7) | 41.1 (152.9) |
| Prior cardiovascular disease | 1877 (20.1) | 940 (20.1) | 937 (20.0) |
| Total cholesterol (mg/dL) | 190.1 (41.2) | 190.2 (41.4) | 190.0 (40.9) |
| Fasting HDL-C (mg/dL) | 52.9 (14.5) | 52.9 (14.3) | 52.8 (14.6) |
| Fasting LDL-C (mg/dL) | 112.4 (35.1) | 112.6 (35.4) | 112.2 (34.8) |
| Fasting total triglycerides (mg/dL) | 125.9 (90.5) | 124.8 (85.8) | 127.1 (95.0) |
| Fasting plasma glucose (units) | 98.8 (13.5) | 98.8 (13.7) | 98.8 (13.4) |
| Statin use | 4052 (43.3) | 1977 (42.3) | 2075 (44.3) |
| Aspirin use | 4756 (51.0) | 2405 (51.6) | 2351 (50.4) |
| 10-Year Framingham risk (%) | 20.1 (10.9) | 20.1 (10.9) | 20.1 (10.8) |
| Body mass index (kg/m2) | 29.9 (5.8) | 29.9 (5.8) | 29.8 (5.7) |
| Smoking | |||
| Never smoker | 4196 (45.0) | 2097 (45.0) | 2098 (45.0) |
| Former smoker | 3898 (41.8) | 1929 (41.4) | 1969 (42.2) |
| Current smoker | 1239 (13.3) | 639 (13.7) | 600 (12.9) |
| Gait speed (m/s) (only for age ≥75 yrs) |
0.87 (0.22) | 0.87 (0.22) | 0.87 (0.21) |
| Logical Memory I | 19.1 (4.9) | 19.1 (4.9) | 19.2 (4.9) |
| Logical Memory II | 8.2 (3.4) | 8.1 (3.4) | 8.2 (3.3) |
| Digit Symbol | 50.8 (15.3) | 50.7 (15.3) | 50.8 (15.4) |
| Montreal Cognitive Assessment (MoCA) | 22.9 (4.1) | 22.9 (4.1) | 22.9 (4.1) |