. Author manuscript; available in PMC: 2015 Oct 1.

Published in final edited form as: Clin Trials. 2014 Jun 5;11(5):565–575. doi: 10.1177/1740774514536000

Table 3.

Standardized Total, Direct, and Indirect Effects

	Total Effect	Direct Effect	Indirect Effect
*Outcome: Enrollment in NCI-Sponsored Cancer Clinical Trials in 2011*

Physician Attitudes Construct	0.130^*	0.130^*	N/A
Organizational Context Construct	0.205^*	0.185^*	0.020
Age	−0.301^*	−0.271^*	−0.030
Hospital-Based^{^}	−0.024	−0.040	0.016
Solo Practice^{^}	0.000	−0.004	0.004
Non U.S. Trained	0.004	−0.004	0.007
PI	0.360^*	0.350^*	0.010
Tenure	0.251^*	0.214	0.037
Hematologist Oncology⁺	−0.127	−0.134	0.007
Radiation Oncology⁺	−0.132	−0.103	−0.029
Surgery⁺	−0.089	−0.076	−0.013
Other Specialty⁺	−0.146^*	−0.135^*	−0.011

Model Fit Statistics: CFI=0.936; TLI= 0.914; RMSEA=0.030; SRMR=0.046

Note: Total effects is the sum of direct and indirect effects

Note: Indirect effects are the product of the regression coefficients leading to the outcome. For example for organizational context, context predicts attitudes and attitudes predicts enrollment. The indirect effect of context on enrollment equals the product of the two regression coefficients (From Figure 3)

0.157*0.130=0.020

Statistically Significant (p<0.05)

^{^}

Compared to Group Practice

⁺

Compared to General Non-Specialized Oncology