TABLE 5.
Reactivities of M. leprae CFP-10-specific T-cell hybridomas to M. leprae CFP-10 and M. leprae and M. tuberculosis peptides p1 and p2
| T-cell hybridoma | Reactivity
|
||||
|---|---|---|---|---|---|
| M. leprae CFP-10 | M. leprae p1 | M. leprae p2 | M. tuber- culosis p1 | M. tuber- culosis p2 | |
| 1G4 | +a | ++ | + | + | − |
| 6G7 | + | +++ | ++ | − | − |
| 5D4 | + | − | ++ | − | − |
| 8D11 | ++ | − | ++ | − | − |
a
+++, optical density, >4.00; ++, optical density, 1.00 to 3.99; +, optical density, 0.20 to 0.99; −, background reading (optical density, <0.20; corresponds to <1 pg of IL-2 per ml). An optical density of >1.00 indicates production of >20 pg of IL-2 per ml by T-cell hybridomas.