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. Author manuscript; available in PMC: 2015 Oct 10.
Published in final edited form as: J Control Release. 2014 Jul 19;191:90–97. doi: 10.1016/j.jconrel.2014.07.038

Figure 2.

Figure 2

Bio-distribution of gold NM and NS in mice with large tumors (<1000 mm3). A) Mean gold content in organs after 4 h intravenous injection. B) Mean gold content in organs after 24 h intravenous injection and C) Mean gold content in organs after 72 h intravenous injection. D) Mean number of gold nanoparticles in the tumor per gram of wet tissue. Gold concentrations were analyzed by ICP-MS. The number of nanoparticles was calculated considering the mass of Au in a NM = 5.22 × 10-9 μg for NM dimensions [r1, r2, r3] = [21, 31, 44] nm and for NS = 1.62 × 10-8 μg of Au for NS with dimensions [r1, r2] = [62, 76] nm. The gold content in tumors in μg of Au/g of wet tissue is plotted as log10 scale for visual clarity of values in organs with low gold content. Error bars are drawn with standard error of mean.