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. Author manuscript; available in PMC: 2015 Sep 6.
Published in final edited form as: Clin Trials. 2014 Mar 6;11(3):328–335. doi: 10.1177/1740774514522561

Table 4.

Identified focus group themes and example quotes.

Motivations to Participate in Clinical Trials
 Hope that participation in the clinical trials will provide options: “… [if] there is a small piece of hope that you can get better, then you should do it.”
 Future family benefits. “I guess family must be the strongest motivation [to participate in clinical trials].”
 Being sick enough that participants will try options not previously considered. “If I do not have a disease, I do not want to do it [be in a clinical trial].”
 The absence of health risks. “If there is no risk to my life, I am willing to participate.”
 Recommendation from a doctor/health care provider. “I will ask the doctor, and rely on doctor's guidance.”
 Making a contribution to future. “To make the next generation better than our lives, we are better to be taking that new medicine and testing it.”
 Perception that younger participants may be more knowledgeable about and interested in clinical trials.
Barriers to participation in clinical trials
 Perception that placebos are the only option for clinical trials. “… If I am given a placebo, that means I am wasting my time for the treatment.”
 Lack of trust in health care professionals: “Although the doctor says it is no problem, I am still worried and afraid …”
Mixed Opinions
 All participants said “no” to the question of religion or culture having an influence. Later discussions included “others” that had beliefs that would be both for and against clinical trials.
 Some participants thought incentives would be beneficial and others thought unnecessary.
What Participants Want to Know about Clinical Trials:
 If the [drug] trial has been successfully tested on animals
 Side effects of the drug
 Success rates of the drug
 How the drug works
 The type of research that has already been completed
 The organization that conducted the research
 How long they can expect to live after the medication
 How much it would cost to participate
How to Promote Clinical Trials
 “Word of mouth” with a good reputation for the group conducting the clinical trial.
 Partnering with community representatives to conduct outreach to subpopulations.
 Common communication channels like brochures, flyers, radio, TV and newspapers.
 Health educators talking to small groups, public discussion forums or workshops.
 Having outreach tables or booths at community events or integrated into health fairs and other community activities.