TABLE 2.
Comparison of antibody responses of individuals susceptible to and protected against P. falciparum infection during the course of the study
Antigen | Prevalencea
|
Antibody levelb
|
||||
---|---|---|---|---|---|---|
Protected (n = 31) | Susceptible (n = 48) | Pc | Protected (n = 31) | Susceptible (n = 48) | Pd | |
RAMA-A | 16.13 | 12.50 | 0.744 | 0.490 (0.340, 0.690) | 0.350 (0.200, 0.460) | 0.016 |
RAMA-B | 67.74 | 58.33 | 0.480 | 0.120 (0.025, 0.630) | 0.095 (0.000, 0.520) | 0.691 |
RAMA-C | 70.97 | 79.17 | 0.430 | 0.570 (0.165, 1.480) | 0.575 (0.260, 1.200) | 0.916 |
RAMA-D | 90.32 | 87.50 | 1.000 | 0.890 (0.300, 1.505) | 0.875 (0.415, 1.505) | 0.511 |
RAMA-E | 80.65 | 85.42 | 0.757 | 1.070 (0.345, 1.735) | 0.365 (0.145, 1.020) | 0.062 |
Percentage of positive sera defined as those that gave OD values greater than the cutoff OD.
Antibody levels are presented as median OD values (lower quartile, upper quartile).
Antibody prevalences of protected and susceptible groups were compared using Fisher's exact test.
Antibody levels of protected and susceptible groups were compared using the Mann-Whitney test.