Figure 3.

Effect of dexamethasone and Cd either alone or in combination on insulin resistance in terms of (a) serum insulin levels, (b) FIRI, and (c) protein expression of insulin receptor in granulosa cell lysate using beta actin as internal control in rats. The values are represented as mean ± SEM of three independent observations (n = 6). Serum insulin levels and FIRI were significantly increased (***P < 0.001 and ^### P < 0.001) in Dexa group as compared to control and Cd group. Dexa + Cd also showed significant increase (***P < 0.001 and  ^### P < 0.001) in serum insulin and FIRI as compared to control and Cd group. Dexa = dexamethasone.