TABLE 1.
Distribution of Vκ and Vλ genes in the nonproductive and productive repertoires from B220+ splenocytes obtained from HEL- or protein L-treated mice
| Gene | % Distribution (n)a |
|||
|---|---|---|---|---|
| Nonproductive rearrangements |
Productive rearrangements |
|||
| HEL | Protein L | HEL | Protein L | |
| Vκ | ||||
| 1D-12 | 21.5 (19) | 28.6 (28) | 26.3 (19) | 16.7* (18) |
| 3D-11 | 0 (19) | 0 (28) | 10.5 (19) | 0* (18) |
| 4-1 | 73.7 (19) | 64.3 (28) | 57.9 (19) | 50* (18) |
| 5-2 | 5.3 (19) | 7.1 (28) | 5.3 (19) | 33.3* (18) |
| Vλ | ||||
| 2 | 70 (20) | 62 (29) | 41.7 (24) | 44.4 (36) |
| 3 | 10 (20) | 20.7 (29) | 54.2 (24) | 55.6 (36) |
| 4 | 20 (20) | 17.2 (29) | 4.2 (24) | 0 (36) |
a
*, P < 0.01. P values were determined within each type of rearrangement by the χ2 test.