FIG. 1.

Enhanced pathogen burden in B. burgdorferi-infected MyD88^−/− mice. B. burgdorferi flaB DNA was quantified in the urinary bladder of individual mice by real-time PCR. Each data point represents the result from an individual mouse normalized to the amount of host β-actin. At both 14 and 45 days after infection, urinary bladders from MyD88^−/− mice harbored significantly more DNA than those from WT mice (13-fold increase at day 14 [P = 0.0079 by the Mann-Whitney test] and 267-fold increase at day 45 [P = 0.0317 by the Mann-Whitney test]).