TABLE 2.

MyD88^−/− macrophages produce TNF-α after exposure to opsonized, but not unopsonized, B. burgdorferi

Stimulus	TNF-α level (pg/ml)a
	WT mice	MyD88−/− mice
None	<100	<100
Unopsonized B. burgdorferi	2,510 ± 43	<100
Opsonized B. burgdorferi	4,550 ± 411	2,750 ± 64b

^aValues are means of triplicate samples ± standard errors of the means.

^bSignificantly different (P = 0.01) from the value for WT samples, as calculated by Student's t test.