Table 2.
Diagnostic accuracy results of individual studies using the immunochromatography method, including the commercial kit Dengue NS1 Ag STRIP Kit and SD BIOLINE Dengue Duo Strip Kit
| Author (year) | Geography | Design | Size (time) | Confirmed testsa | TP | FP | FN | TN | Sensitivity % (95% CI) | Specificity % (95% CI) | PPV % | NPV % | QUADAS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Shu et al. (2009)b | Asia | Retrospective | 162 (15/30 min) | 4 | 82 | 0 | 40 | 50 | 67 (58–75) | 100 (93–100) | 100 | 56 | 7 |
| Ramirez et al. (2009)b | South America (Venezuela) | Retrospective | 147 (30 min) | 1 | 59 | 2 | 28 | 58 | 68 (57–77) | 97 (88–100) | 97 | 67 | 8 |
| Zainah et al. (2009)b | Southeast Asia (Malaya) | Retrospective | 533 (15/30 min) | 1 | 284 | 1 | 30 | 218 | 49 (43–56) | 100 (97–100) | 100 | 88 | 9 |
| Osorio et al. (2010)c | Southeast Asia (Colombia) [Au?16] | Retrospective | 400 (NR) | 1 | 111 | 3 | 107 | 89 | 51 (44–58) | 97 (91–99) | 97 | 45 | 11 |
| Lima et al. (2010)b | South America (Brazil) | Prospective | 550 (15/30 min) | 1 | 197 | 2 | 23 | 228 | 90 (85–93) | 99 (97–100) | 99 | 91 | 10 |
| Pok et al. (2010)b | Europe (Singapore) [Au?16] | Prospective | 209 (NR) | 2 | 86 | 1 | 23 | 99 | 79 (70–86) | 99 (95–100) | 99 | 81 | 8 |
| Chaterji et al. (2011)b | Europe (Singapore) [Au?16] | Prospective | 354 (15 min) | 3 | 119 | 0 | 35 | 200 | 77 (70–86) | 100 (98–100) | 100 | 85 | 10 |
| Chaterji et al. (2011)b | Europe (Singapore) [Au?16] | Prospective | 354 (30 min) | 3 | 124 | 0 | 30 | 200 | 77 (70–84) | 100 (98–100 | 100 | 87 | 10 |
| Najioullah et al. (2011)b | North America (Martinique) | Prospective | 537 (30 min) | 4 | 125 | 0 | 128 | 272 | 81 (73–86) | 100 (99–100) | 100 | 68 | 10 |
| Blacksell et al. (2011)b | Asia (Sri Lanka) | Prospective | 259 (NR) | 2 | 58 | 2 | 41 | 158 | 90 (87–93) | 99 (96–100) | 97 | 79 | 10 |
| Blacksell et al. (2011)b | Asia (Sri Lanka) | Prospective | 259 (NR) | 2 | 58 | 12 | 41 | 148 | 59 (48–68) | 93 (87–96) | 83 | 78 | 10 |
| Blacksell et al. (2011)c | Asia (Sri Lanka) | Prospective | 259 (NR) | 2 | 48 | 1 | 51 | 159 | 48 (38–59) | 99 (97–100) | 98 | 76 | 10 |
TP, true positive; FP, false positive; FN, false negative; TN, true negative; CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value; QUADAS, Quality Assessment for Diagnostic Accuracy Studies; NR, not reported.
a
Confirmed tests: (1) serological, nucleotide, or viral culture test; (2) serological or nucleotide test; (3) viral culture or nucleotide test; (4) nucleotide test.
b
Statistics retrieved from studies using the Dengue NS1 Ag STRIP Kit.
c
Statistics retrieved from studies using the SD BIOLINE Dengue Duo Strip Kit.