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. Author manuscript; available in PMC: 2015 Sep 15.
Published in final edited form as: J Immunol. 2014 Aug 4;193(6):2919–2930. doi: 10.4049/jimmunol.1400980

Figure 3. SEB-induced systemic cytokine/chemokine surge in naïve and IL-2-anti-IL-2 complex-treated HLA-DR3 transgenic.

Figure 3

HLA-DR3 transgenic mice were left untreated or injected with immune complexes comprising of IL-2 and anti-IL-2 antibodies on days 0, 1 and 2 (3xIL2C). On day 5, mice were challenged with SEB (50 µg/mouse) or PBS and bled 3 hours later. Concentrations of indicated cytokines/chemokines were determined using multiplex assay. Each bar represents mean±SE of data obtained from 6–8 mice in each group. * p<0.05 compared to naïve mice.