Table 2.
Risk Factors in the Final Multiple Logistic Regression Models for the Adverse Pregnancy Outcomes*
| Risk Factor | PT OR (95% CI) |
LBW OR (95% CI) |
SGA OR (95% CI) |
SB# OR (95% CI) |
APOs OR (95% CI) |
|---|---|---|---|---|---|
| Age of mother at delivery (years) | |||||
| <25 | 0.95 (0.27 – 3.35) | ||||
| 25 – 29 | 1.00 | ||||
| >29 | 2.89 (1.05 – 7.90) | ||||
| BMI at or near delivery adjusted by GA (kg/m2) | |||||
| Low ( <18.5) | 2.87 (1.72 – 4.79) | 3.25 (2.01 – 5.27) | 2.23 (1.43 – 3.46) | ||
| Normal (18.5–24.9) | 1.00 | 1.00 | 1.00 | ||
| High ( ≥ 25) | 0.60 (0.40 – 0.91) | 0.40 (0.26 – 0.64) | 0.63 (0.48 – 0.84) | ||
| History of previous preterm birth | |||||
| Yes | 1.92 (1.29 – 2.85) | ||||
| No | 1.00 | ||||
| Hospitalization during pregnancy | |||||
| Yes | 3.56 (2.29 – 5.52) | 2.33 (1.27 – 4.26) | 3.25 (1.98 – 5.34) | ||
| No | 1.00 | 1.00 | 1.00 | ||
| Hypertension during pregnancy | |||||
| Yes | 3.73 (1.96 – 7.10) | 2.79 (1.36 – 5.74) | 2.72 (1.54 – 4.80) | ||
| No | 1.00 | 1.00 | 1.00 | ||
| Lower respiratory tract infection (LRTI ) during pregnancy | |||||
| Yes | 2.34 (1.03 – 5.31) | 4.13 (1.10 – 15.58) | |||
| No | 1.00 | 1.00 | |||
| Most complex ARV regimen received at least 28 days during 3rd trimester | |||||
| HAART with PI | 0.59 (0.28 – 1.26) | 0.14 (0.05 – 0.34) | |||
| HAART w/o PI | 0.33 (0.14 – 0.74) | 0.11 (0.04 – 0.34) | |||
| Non HAART | 0.40 (0.15 – 1.05) | ||||
| No ARVs or ARVs<28 Days | 1.00 | 1.00 | |||
| Receipt of ARVs at conception | |||||
| Yes | 1.53 (1.11 – 2.09) | 1.40 (1.04 – 1.87) | |||
| No | 1.00 | 1.00 | |||
| Plasma HIV-1 RNA concentration at hospital discharge (copied/ml) | |||||
| ≥ 400 | 1.47 (1.07 – 2.03) | ||||
| <400 | 1.00 | ||||
| Reason for receiving ARVs during pregnancy | |||||
| Treatment | 1.80 (1.26 – 2.56) | ||||
| Prophylaxis | 1.00 | ||||
| Tobacco use during pregnancy | |||||
| Yes | 1.78 (1.24 – 2.54) | 1.71 (1.30 – 2.24) | |||
| No | 1.00 | 1.00 | |||
*
Since none of the participants that had a SB used a non-HAART regimen during the third trimester, subjects that did not have a SB that used non-HAART during the third trimester were excluded from the model in order to fit this predictor.
#
Abbreviations: PT for preterm delivery; LBW for low birth weight; SGA for small for gestational age; SB for stillbirth; APOs for adverse pregnancy outcomes; OR for adjusted odds ratio for the other risk factors in the models and CI for confidence interval.