Table 4.

Effects of Race and Age upon Quality of Life (QOL)

Domain			N	SD	Min	Median	Max	95% CI	p-value*
White
	Negative Feelings	846	11.2	4.2	4	10	28	10.9 – 11.5	0.4065
rev	Positive Feelings	799	10.7	5.0	4	10	28	10.4 – 11.1	0.5147
	Cognitive Problems	826	12.0	5.0	4	11	28	11.6 – 12.3	0.1566
	Physical Pain	822	9.3	5.2	4	8	28	9.0 – 9.7	0.0626
	Sexual Interest	803	7.4	3.8	2	7	14	7.2 – 7.7	0.1343
	Sexual Function	819	6.3	3.6	2	6	14	6.1 – 6.5	0.0988
rev	Fatigue a	830	12.1	5.3	4	11	27	11.7 – 12.5	0.0523
	Social Avoidance	798	8.8	4.9	4	8	28	8.5 – 9.2	0.0058
	Financial Problems	825	9.5	6.5	4	7	28	9.1 – 9.9	0.0010
rev	Benefits of Cancer	830	12.9	6.0	4	12	28	12.4 – 13.3	0.0105
	Distress about Family b	834	12.9	6.9	4	10.7	28	12.5 – 13.4	0.0028
	Appearance Concerns	822	11.6	6.0	4	10	28	11.2 – 12.0	0.5331
	Distress about Recurrence	816	13.7	6.2	4	12	28	13.3 – 14.1	0.5284
	Summary Score: Generic c	721	77.0	26.7	28	73	166	75.1 – 79.0	0.3701
	Summary Score: Cancer Specific d	785	44.1	17.9	15	41	102	42.8 – 45.3	0.0086
Spanish / Hispanic
	Negative Feelings	106	11.6	5.2	4	11	26	10.6 – 12.6	---
rev	Positive Feelings	102	10.0	5.7	4	8	26	8.8 – 11.1	---
	Cognitive Problems	106	12.3	5.7	4	11	28	11.2 – 13.4	---
	Physical Pain	105	9.7	5.	4	9	25	8.7 – 10.7	---
	Sexual Interest	98	6.7	4.1	2	6	14	5.9 – 7.5	---
	Sexual Function	103	6.0	3.8	2	5	14	5.3 – 6.7	---
rev	Fatigue a	106	12.6	5.6	4	12	28	11.5 – 13.7	---
	Social Avoidance	97	9.6	5.6	4	8	26	8.4 – 10.7	---
	Financial Problems	103	11.2	7.1	4	9	28	9.8 – 12.5	---
rev	Benefits of Cancer	107	11.1	6.5	4	9	28	9.9 – 12.4	---
	Distress about Family b	109	15.2	7.7	4	13.3	28	13.8 – 16.7	---
	Appearance Concerns	104	12.2	6.3	4	11.5	28	11.0 – 13.4	---
	Distress about Recurrence	104	14.5	6.7	4	14	28	13.2 – 15.8	---
	Summary Score: Generic c	83	80.0	32.7	29	74	168	72.8 – 87.1	---
	Summary Score: Cancer Specific d	96	49.1	18.9	15	45.5	102	45.3 – 53.0	---
Black
	Negative Feelings	88	12.0	5.5	4	10.5	26	10.8 – 13.1	---
rev	Positive Feelings	84	10.5	5.4	4	9	25	9.3 – 11.7	---
	Cognitive Problems	88	12.5	6.2	4	11	27	11.2 – 13.8	---
	Physical Pain	87	10.9	6.7	4	9	27	9.5 – 12.3	---
	Sexual Interest	88	6.9	4.0	2	6	14	6.0 – 7.7	---
	Sexual Function	90	5.4	3.7	2	4	14	4.6 – 6.1	---
rev	Fatigue a	91	13.2	5.9	4	12	26	11.9 – 14.4	---
	Social Avoidance	87	10.8	6.7	4	9	28	9.4 – 12.2	---
	Financial Problems	90	12.1	7.6	4	10	28	10.5 – 13.7	---
rev	Benefits of Cancer	90	11.4	5.9	4	11	28	10.2 – 12.7	---
	Distress about Family b	91	14.7	7.6	4	12	28	13.1 – 16.2	---
	Appearance Concerns	89	12.1	6.6	4	11	28	10.7 – 13.5	---
	Distress about Recurrence	90	14.1	6.4	4	13	28	12.7 – 15.4	---
	Summary Score: Generic c	70	81.3	36.2	33	67.5	173	72.6 – 89.9	---
	Summary Score: Cancer Specific d	85	49.1	20.4	15	47	105	44.7 – 53.5	---
Asian / Pacific Islander
	Negative Feelings	36	11.6	4.4	4	11	25	10.1 – 13.1	---
rev	Positive Feelings	35	10.3	4.6	4	10	20	8.8 – 11.9	---
	Cognitive Problems	37	10.3	4.4	4	9	21	8.8 – 11.7	---
	Physical Pain	37	9.3	5.0	4	8	28	7.6 – 11.0	---
	Sexual Interest	34	6.6	3.6	2	6	14	5.4 – 7.9	---
	Sexual Function	35	5.8	3.2	2	5	14	4.7 – 6.9	---
rev	Fatigue a	37	10.4	4.9	4	10	23	8.8 – 12.0	---
	Social Avoidance	35	9.5	3.9	4	9	17	8.2 – 10.8	---
	Financial Problems	35	9.7	6.1	4	9	23	7.7 – 11.8	---
rev	Benefits of Cancer	37	12.3	6.3	4	13	25	10.2 – 14.4	---
	Distress about Family b	37	12.6	6.4	4	12	28	10.5 – 14.8	---
	Appearance Concerns	37	10.8	5.6	4	10	24	8.9 – 12.7	---
	Distress about Recurrence	37	13.1	6.6	4	12	28	10.9 – 15.3	---
	Summary Score: Generic c	31	72.4	27.2	34	68	153	62.4 – 82.3	---
	Summary Score: Cancer Specific d	35	42.8	20.4	15	40	92	35.8 – 49.8	---
Age < 40 Years
	Negative Feelings	441	11.7	4.5	4	11	26	11.2 – 12.1	0.0532
rev	Positive Feelings	426	10.6	5.1	4	10	28	10.2 – 11.1	0.9024
	Cognitive Problems	443	12.1	5.3	4	12	26	11.6 – 12.5	0.6642
	Physical Pain	443	9.0	5.2	4	8	28	8.6 – 9.5	0.0300
	Sexual Interest	430	6.8	3.9	2	6	14	6.5 – 7.2	0.0016
	Sexual Function	442	5.9	3.5	2	5	14	5.6 – 6.2	0.0523
rev	Fatigue a	445	12.1	5.2	4	11	27	11.6 – 12.6	0.6441
	Social Avoidance	431	9.1	5.2	4	8	28	8.6 – 9.6	0.9173
	Financial Problems	441	10.2	6.9	4	8	28	9.6 – 10.9	0.1400
rev	Benefits of Cancer	444	12.1	6.0	4	11	28	11.6 – 12.7	0.0484
	Distress about Family b	447	13.5	7.1	4	12	28	12.9 – 14.2	0.3587
	Appearance Concerns	442	12.0	6.1	4	11	28	11.4 – 12.6	0.1234
	Distress about Recurrence	435	14.3	6.5	4	13	28	13.6 – 14.9	0.0498
	Summary Score: Generic c	390	77.3	28.3	28	71.5	166	74.5 – 80.1	0.9011
	Summary Score: Cancer Specific d	417	46.2	18.7	15	44	102	44.4 – 48.0	0.0611
Age ≥ 40 Years
	Negative Feelings	614	11.1	4.4	4	10	28	10.8 – 11.5	---
rev	Positive Feelings	598	10.6	5.1	4	9	25	10.2 – 11.0	---
	Cognitive Problems	618	11.9	5.2	4	11	28	11.5 – 12.3	---
	Physical Pain	612	9.8	5.4	4	8	28	9.3 – 10.2	---
	Sexual Interest	597	7.6	3.8	2	7	14	7.3 – 7.9	---
	Sexual Function	609	6.4	3.7	2	6	14	6.1 – 6.6	---
rev	Fatigue a	623	12.2	5.6	4	11	28	11.8 – 12.7	---
	Social Avoidance	590	9.1	5.1	4	8	28	8.7 – 9.5	---
	Financial Problems	616	9.6	6.6	4	7	28	9.1 – 10.1	---
rev	Benefits of Cancer	624	12.9	6.1	4	12	28	12.4 – 13.3	---
	Distress about Family b	628	13.1	7.0	4	10.7	28	12.6 – 13.7	---
	Appearance Concerns	614	11.4	6.0	4	10	28	10.9 – 11.9	---
	Distress about Recurrence	616	13.5	6.0	4	12	28	13.0 – 14.0	---
	Summary Score: Generic c	519	77.5	28.0	28	73	173	75.1 – 80.0	---
	Summary Score: Cancer Specific d	588	44.0	18.1	15	40	105	42.5 – 45.5	---

^a(reverse Q1) + Q5 + Q11 + Q14

^bQ31 + Q34 + Q42 +Mean(Q31, Q34, Q42)

^cSum (Negative Feelings Subscale, Positive Feelings Subscale (reversed), Cognitive Problems Subscale, Physical Pain Subscale, Sexual Problems Subscale, Energy/Fatigue Subscale (reverse Q1), Social Avoidance Subscale)

^dSum (Financial Subscale, Distress Family Subscale (Q31 + Q34 + Q42), Appearance Subscale, Distress Recurrence Subscale)

^*p-value for comparing scores for patients age < 40 years at diagnosis versus patients age ≥ 40 years at diagnosis. Using a Bonferroni correction due to performance of 15 tests suggests using a significance level of 0.05/15 = 0.0033 for each test.