Figure 1.

Pedigree and Olfactory MRI of the Probands

(A) Pedigrees of the families; arrows point to probands. Solid symbols indicate affected family members, open symbols indicate unaffected family members, squares indicate male family members, circles indicate female family members, and the double line indicates consanguinity. Under each symbol is the FEZF1 genotype.

(B) Brain MRI at T2 coronal sections. The left panel is from a healthy young adult; the arrow indicates normal olfactory bulbs. The middle panel shows the absence of olfactory bulbs (aplasia) in the proband from family 1. The right panel demonstrates the absence of olfactory bulbs (aplasia) in the proband from family 2.