Table 1.
Ratiosb |
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---|---|---|---|---|---|---|---|
Subjecta | Age, yr | RBC:barrier | TLCc, liters | DLCOc, ml·min−1·mmHg−1 | RBC:gas | Barrier:gas | Lung Inflation, % |
Healthy | |||||||
1 | 59 | 0.47 | 0.002 | 0.005 | 7.6 | 23.3 | 59.1 |
2 | 65 | 0.47 | 0.003 | 0.006 | 7.2 | 28.1 | 62.6 |
3 | 51 | 0.35 | 0.002 | 0.007 | 5.7 | 21.5 | 74.9 |
4 | 24 | 0.79 | 0.003 | 0.004 | 6.7 | 26.6 | 66.3 |
5 | 33 | 0.57 | 0.003 | 0.005 | 8.0 | 31.8 | 68.6 |
6 | 29 | 0.43 | 0.003 | 0.007 | 6.3 | 27.8 | 61.7 |
7 | 27 | 0.65 | 0.005 | 0.008 | 7.2 | 42.7 | 54.6 |
8 | 23 | 0.53 | 0.007 | 0.014 | 7.3 | 31.9 | 46.7 |
9 | 22 | 0.69 | 0.006 | 0.009 | 9.2 | 29.8 | 54.9 |
10 | 56 | 0.52 | 0.004 | 0.007 | 6.6 | 25.7 | 70.3 |
11 | 65 | 0.53 | 0.004 | 0.008 | 7.0 | 30.1 | 59.7 |
IPF | |||||||
1 | 74 | 0.13 | 0.002 | 0.012 | 4.2 | 10.8 | |
2 | 83 | 0.22 | 0.003 | 0.013 | 4.7 | 12.6 | |
3 | 54 | 0.17 | 0.003 | 0.016 | 3.8 | 11.2 | |
4 | 51 | 0.14 | 0.002 | 0.011 | 3.3 | 7.2 | |
5 | 72 | 0.16 | 0.001 | 0.008 | 4.1 | 9.4 | |
6 | 67 | 0.16 | 0.001 | 0.009 | 3.8 | 9.4 |
All subjects were male, except subject 3. bRatios were measured in the supine position. cPulmonary function data were measured in the upright position. IPF, idiopathic pulmonary fibrosis; RBC, red blood cell; TLC, total lung capacity; DLCO, lung diffusing capacity for carbon monoxide.