Table 4. Histopathology summary.

Summary statistics for histopathological observations on all apparently healthy (n = 21), diseased (n = 11), and mitigation treatment samples (n = 11). Condition scores applied were 0 = Excellent, 1 = Very Good, 2 = Good, 3 = Fair, 4 = Poor, 5 = Very Poor; scoring of severity or intensity of tissue changes from normal were 0 = Within Normal Limits, 1 = Minimal, 2 = Mild, 3 = Moderate, 4 = Marked, 5 = Severe.

Parameter	Apparently healthy			Characterization diseased			Mitigation treatments
Assigned scores	Mean	St.Dev.	Range	Mean	St.Dev.	Range	Mean	St.Dev.	Range
General condition (100×)	1.6	0.7	1–3	4.5	0.5	3–5	4.4	0.7	3–5
Zooxanthellae (100×)	1.2	0.5	0–2	3.6	0.4	3–4	3.4	0.3	3–4
Epidermal mucocytes condition	1.7	0.5	1–2	4.3	0.5	3–5	4.3	0.6	3–5
Mesenterial filament mucocytes	2.7	1.1	1–5	4.4	0.7	3–5	4.2	0.9	2–5
Degeneration cnidoglandular bands	1.5	1.3	0–5	4.3	1.0	2–5	3.8	1.3	2–5
Dissociation mesenterial filaments	0.5	0.9	0–3	2.8	1.5	0–5	1.9	1.2	0.2–3.7
Costal tissue loss	0.3	0.5	0–1	3.5	1.3	1–5	3.2	1.4	0.9–4.8
Calicodermis condition	1.4	0.6	1–3	4.0	0.7	2–5	3.8	0.9	2.1–4.9
Bacterial aggregates	0.0	0.0	0–0	0.0	0.0	0–0	0.0	0.0	0–0
Epidermal RLOs	3.2	0.6	2–4	3.6	0.5	3–4	3.4	0.5	2.5–4
Filament RLOs	2.8	0.5	2–4	2.8	1.2	1–5	2.9	0.9	2–5
Percent affected (presence/absence)
Coccidia	10			14			10
Calicodermis repair	0			43			33
Necrotic cell spherules	0			33			33
Zooxanthellate ciliates	0			24			24
Non-zooxanthellate ciliates	0			10			14
Oocytes	10			10			5
Spermaries	0			0			0