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. Author manuscript; available in PMC: 2014 Sep 8.
Published in final edited form as: Genet Epidemiol. 2014 May 5;38(5):389–401. doi: 10.1002/gepi.21798

Figure 1.

Figure 1

Power as a function of the between-study heterogeneity for the quantitative trait. The left, middle, and right panels correspond to three different genetic structures: (a) genetic effects exhibit at the burden score level for variants with MAFs< 5%, (b) genetic effects exhibit at the burden score level for variants with MAFs< 1%, and (c) genetic effects exhibit at the individual variant level. For each structure, 80%, 50% or 20% of the variants in ten 300 base-pair regions were randomly selected to be potentially causal.