Table 2.
Analysis of positive selection in five Borrelia species.
| Locus | 2*Delta-likelihood |
Statistical significance |
Function | |||
|---|---|---|---|---|---|---|
| M1a vs. M2a | M7 vs. M8 | M8 vs. M8a | No. of methods | Level | ||
| 1 | 47.95 | 52.16 | 47.20 | 3 | 0.01 | Chemotaxis protein methyltransferase 287 aa |
| 2 | 24.64 | 27.71 | 26.94 | Chromate transport protein, putative 192 aa | ||
| 3 | 19.87 | 24.40 | 19.95 | Uncharacterized conserved protein 272 aa | ||
| 4 | 13.59 | 16.44 | 14.91 | Conserved hypothetical integral membrane protein 293 aa | ||
| 5 | 13.43 | 21.33 | 12.10 | Uncharacterized conserved protein 302 aa | ||
| 6 | 13.10 | 15.23 | 14.39 | Carboxypeptidase, putative 280 aa | ||
| 7 | 12.90 | 14.74 | 13.82 | Phosphomevalonate kinase, putative 313 aa | ||
| 8 | 12.44 | 16.77 | 14.02 | Chemotaxis response regulator 136 aa | ||
| 9 | 11.42 | 16.25 | 12.59 | Uncharacterized conserved protein 260 aa | ||
| 10 | 10.86 | 11.04 | 10.05 | S-adenosylmethionine synthetase 389 aa | ||
| 11 | 10.52 | 13.30 | 12.23 | UDP-N-acetylglucosamine–N-acetylmuramyl-(pentapeptide) | ||
| 12 | 10.21 | 14.66 | 10.12 | Uncharacterized conserved protein 273 aa | ||
| 13 | 9.68 | 13.29 | 8.37 | ATPase involved in DNA repair 528 aa | ||
| 14 | 9.69 | 11.77 | 9.78 | Holo-acyl-carrier protein synthase 129 aa | ||
| 15 | 8.67 | 19.49 | 9.99 | 3 | 0.05 | CTP synthase 551 aa |
| 16 | 7.54 | 13.99 | 7.68 | Chemotaxis protein CheD 167 aa | ||
| 17 | 7.32 | 12.10 | 7.92 | l-Lactate dehydrogenase 320 aa | ||
| 18 | 7.01 | 11.35 | 5.23 | Uncharacterized conserved protein 422 aa | ||
| 19 | 6.67 | 10.71 | 8.80 | tRNA pseudouridine 55 synthase 281 aa | ||
| 20 | 6.65 | 7.91 | 7.76 | HemN-related protein 379 aa | ||
| 21 | 6.52 | 16.42 | 6.70 | Uncharacterized conserved protein 257 aa | ||
| 22 | 6.09 | 11.58 | 8.74 | Exported protein 357 aa | ||
| 23 | 6.00 | 9.77 | 6.50 | Uncharacterized conserved protein 313 aa | ||
| 24 | 6.33 | 7.93 | 6.36 | Flagellar protein 143 aa | ||
| 25 | 8.71 | 6.98 | 4.16 | Signal recognition particle protein 449 aa | ||
| 26 | 50.59 | 18.29 | 3.27 | 2 | 0.01 | Hypothetical protein BDU_209 731 aa |
| 27 | 5.94 | 13.88 | 7.67 | Uncharacterized conserved protein 334 aa | ||
| 28 | 5.47 | 11.08 | 7.45 | Methyl-accepting chemotaxis protein 391 aa | ||
| 29 | 4.48 | 9.35 | 7.18 | DNA gyrase, subunit A 815 aa | ||
| 30 | 5.82 | 9.27 | 6.95 | Flagellar motor rotation protein B 262 aa | ||
| 31 | 5.74 | 11.53 | 6.49 | 2 | 0.05 | Uncharacterized conserved protein 183 aa |
| 32 | 5.80 | 15.34 | 6.19 | Uncharacterized conserved protein 477 aa | ||
| 33 | 4.48 | 6.74 | 6.13 | Uncharacterized conserved protein | ||
| 34 | 5.96 | 12.34 | 6.10 | Lysyl-tRNA synthetase 532 aa | ||
| 35 | 4.08 | 9.73 | 6.08 | ATP-dependent Clp protease, subunit X 429 aa | ||
| 36 | 5.98 | 14.59 | 6.05 | 1-Acyl-sn-glycerol-3-phosphate acyltransferase 250 aa | ||
| 37 | 5.67 | 9.23 | 5.66 | 30S ribosomal protein S5 164 aa | ||
| 38 | 5.46 | 10.80 | 5.43 | Conserved hypothetical GTP-binding protein 368 aa | ||
| 39 | 5.23 | 20.06 | 5.40 | Trigger factor 448 aa | ||
| 40 | 4.52 | 8.65 | 5.21 | Exodeoxyribonuclease V, gamma chain 1070 aa | ||
| 41 | 5.16 | 13.81 | 5.17 | Hemolysin 259 aa | ||
| 42 | 4.49 | 7.03 | 4.51 | Uncharacterized conserved protein 143 aa | ||
| 43 | 4.01 | 15.65 | 4.40 | Translation elongation factor G 674 aa | ||
| 44 | 4.49 | 15.41 | 3.98 | p-512 protein 2361 aa | ||
| 45 | 3.20 | 7.28 | 6.39 | Flagellar protein 389 aa | ||
| 46 | 2.95 | 6.81 | 5.93 | Glycerol-3-phosphate dehydrogenase, NAD(P) 350 aa | ||
| 47 | 3.60 | 8.25 | 5.64 | Hypothetical protein BDU_543 361 aa | ||
| 48 | 2.89 | 7.35 | 5.60 | Phenylalanyl-tRNA synthetase alpha chain 515 aa | ||
| 49 | 3.25 | 6.82 | 5.49 | Uncharacterized conserved protein 492 aa | ||
| 50 | 3.77 | 7.18 | 5.17 | Uncharacterized conserved protein 359 aa | ||
| 51 | 3.05 | 11.02 | 5.07 | DNA helicase 698 aa | ||
| 52 | 1.14 | 6.49 | 3.94 | Purine-binding chemotaxis protein CheW 465 aa | ||
| 53 | 3.07 | 9.44 | 3.91 | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 354 aa | ||
| 54 | 2.84 | 6.41 | 3.90 | 3-Methyladenine DNA glycosylase 196 aa | ||
| 55 | 3.81 | 11.72 | 3.86 | Uncharacterized conserved protein 270 aa | ||
This analysis indicates that 55 chromosomal genes are under positive selection.