Table 2.
Changes over time sleep architecture
| Time 1 | Time 2 | Time 3 | |
|---|---|---|---|
| Baseline: prior to chemotherapy (N = 26) | Approximately 3 weeks following last chemotherapy1 (N = 23) | Approximately 12 weeks following last treatment2 (N = 22) | |
| Stage 1 (SD) P=0.411# | 5.9% (5.1) | 5.2% (3.8) | 6.1% (4.1) |
| Stage 2 (SD) P=0.981# | 67.3% (7.4) | 67.1% (6.4) | 67.5% (6.1) |
| SWS (SD)3 P=0.691# | 2.2% (5.0) | 2.2% (5.1) | 2.4% (4.0) |
| REM sleep (SD) P=0.682# | 21.5% (6.4) | 22.4% (5.1) | 21.7% (5.7) |
Notes: SWS = slow-wave sleep.
1
One of the 23 patients had radiation therapy concurrent with chemotherapy and one patient had a surgical procedure following the completion of chemotherapy and prior to the second PSG assessment.
2
Following last chemotherapy or last radiation treatment if radiation therapy followed the conclusion of chemotherapy.
3
Values for SWS represent a geometric mean (see text).
#
Significance of the time effect using repeated-measures.