Table 4.
Changes over time in fatigue
Time 1 | Time 2 | Time 3 | |
---|---|---|---|
Baseline: prior to chemotherapy (N = 26) | Approximately 3 weeks following last chemotherapy1 (N = 23) | Approximately 12 weeks following last treatment2 (N = 22) | |
Brief Fatigue Inventory (SD) P=0.252# | 2.9 (1.8) | 3.5a (2.4) | 2.7b (2.5) |
Additional Concerns subscale of FACIT3 (SD) P<0.001# | 36.1 (11.1) | 30.2c (13.5) | 38.1d (12.7) |
Single-item measure of fatigue severity (SD) P=0.026# | 3.6 (2.8) | 5.0e (3.4) | 3.8 (3.4) |
Notes:Higher scores on the Additional Concerns subscale of FACIT represent less fatigue and higher scores on the other two measures indicate greater fatigue.
One of the 23 patients had radiation therapy concurrent with chemotherapy, and one patient had a surgical procedure following the completion of chemotherapy and prior to the second PSG assessment.
Following last chemotherapy or last radiation treatment if radiation therapy followed the conclusion of chemotherapy.
Functional Assessment of Chronic Illness Therapy-Fatigue.
Significance of the time effect using repeated-measures.
Significantly different from Baseline at P=0.005.
Significantly different from Time 2, P=0.012.
Significantly different from Baseline at P<0.001.
Significantly different from Time 2, P<0.001.
Significantly different from Baseline, P=0.022.