Figure 1.

Control of HIV-1 by vaccines that stimulate CTLs. Effect of various T cell-stimulating vaccines (key) on viral load over time (with infection on day 0) during natural infection with HIV or SIV, showing the decrease in viral load achieved without a vaccine (none), by CTL responses [partial control; as in Ref. (92), for example], by the RhCMV vaccine (slow eradication) (60, 61) and by a hypothetical vaccine that targets the virus at the site of infection (rapid eradication). Reproduced with permission from Ref. (61).