Figure 4.

Upregulation of TF-1 in response to Zol is TNFα-dependent. PBMC from a healthy donor were cultured in medium with graded dilutions (indicated on the x axis) of either anti-TNFα mAb or control IgG. Cells were stimulated with Zol, with LPS or not stimulated (medium), and TF-1 was measured by flow cytometry as described in Figure 3. Results are representative of three experiments.