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. Author manuscript; available in PMC: 2014 Sep 8.
Published in final edited form as: Cancer Cell. 2009 Jun 2;15(6):539–550. doi: 10.1016/j.ccr.2009.03.027

Figure 3. Mammary cancer incidence in female MMTV-ATX, or MMTV-LPA1, 2, 3 transgenic mice.

Figure 3

Female transgenic mice were bred 3 times to induce the MMTV-LTR promoter and monitored for tumor incidence over 24 months with WT females including FVB/N and nontransgenic littermates as controls. (A) Mammary cancers, large (1.5 × 2.0 × 1.6 cm, black arrowhead) and small (0.5 × 0.5 × 0.5 cm, red arrowhead), developed in MMTV-LPA2. (B) Kaplan-Meyer analysis of mammary cancers. (C) Mammary cancer incidence in each line.