Figure 3.

Striatal Integration of Visual Inputs

(A) Schematics of anterograde tracing (BDA) injection in layer 5 of primary visual cortex and experimental procedure.

(B) Example of ipsilateral axonal projection from visual cortex to striatum. BDA staining: axonal projections (red) and Nissl staining (blue). The inset illustrates the axonal projection fields in striatum (in red) marked on the coronal diagram taken from the Paxinos mouse brain atlas at the AP 0 mm coordinate.

(C) Raw traces of LFP in V1 (top) and simultaneous whole-cell recording in dorsomedial striatum (bottom). Red lines designate the onset of visual stimuli.

(D) Examples of waveform averages of three different simultaneous extra and intracellular recordings as in (C).

(E and F) Average onset and peak delays of evoked visual responses recorded simultaneously in V1 (LFP) and striatum (whole-cell), n = 16.

(G) Morphological reconstruction of a visually responding MSN in dorsomedial striatum. Different scales show the somatic location, morphology, and dendritic spines. Note the somatic location close to the lateral ventricle and white matter, within the field of ipsilateral projections from V1 (B).

Error bars represent the SEM.