Table 3.
Baseline characteristics by diagnosis of oral candidiasis among 454 participants with an interpretable sputum culture in Protocol A5253 (sub-Saharan Africa sites)*
| Characteristic | Oral candidiasis (n = 81) n (%) |
No oral candidiasis (n = 373) n (%) |
P value† |
|---|---|---|---|
| Categorical variables | |||
| Race/ethnicity | |||
| Black non-Hispanic | 81 (100) | 370 (99) | 1.000 |
| Hispanic (any race) | 0 (0) | 2 (1) | |
| Asian/Pacific Islander | 0 (0) | 1 (<1) | |
| Sex | |||
| Female | 53 (65) | 268 (72) | 0.250 |
| Male | 28 (35) | 105 (28) | |
| CD4 cell count, cells/mm3 | |||
| <200 | 55 (68) | 96 (26) | <0.001 |
| 200–500 | 22 (27) | 202 (54) | |
| >500 | 4 (5) | 75 (20) | |
| Currently on antifungal medication | 8 (10) | 28 (8) | 0.496 |
| Continuous variables, median (Q1, Q3)‡ | |||
| Age | 35 (29, 40) | 32 (28, 39) | 0.108 |
| CD4 cell count | 151 (46, 228) | 287 (190, 463) | <0.001 |
*
Among 455 participants with interpretable sputum culture result in African sites in Protocol A5253, 454 underwent an oral examination.
†
Fisher’s exact test for race and CD4 cell count; χ2 test for sex.
‡
P values using Wilcoxon’s rank-sum test.
Q = quartile.