Fig. 9.

Mice were transduced by injecting Ad-CMV-luciferase via the tail vein; the control mice were injected with a control virus without the fluc sequence. Five minutes after tail-vein injection of ¹⁴C-D-luciferin and mass level of carrier D-luciferin, mice were imaged in a CCD camera, and organs were harvested immediately after imaging to measure uptake in %ID/g. In pooled data over six fluc-transfected and five control mice, the difference in ¹⁴C-D-luciferin uptake was only borderline significant (p=0.0047). No higher uptake differences between fluc-transfected and control tissue could be detected at earlier or later time points in similar experiments