Table 3.
White Blood Cell Counts Measured 4 Days after Injection with Saline, Free Docetaxel or C2-NP at Two Dose Levels
| time point | saline | free docetaxel (20 mg/kg) | C2-NP (20 mg/kg) | C2-NP (50 mg/kg) |
|---|---|---|---|---|
| WBC (103 cells/μL) | ||||
| day of dose 1 | 2.07 ± 0.21 | 1.34 ± 0.36 | 1.67 ± 0.54 | 1.54 ± 0.35 |
| 4 days after dose 1 | 2.81 ± 0.91 | c0.84 ± 0.65 | a,c1.41 ± 0.65 | c0.49 ± 0.38 |
| 4 days after dose 6 | 3.43 ± 1.13 | c1.53 ± 0.52 | b3.00 ± 1.10 | c0.56 ± 0.28 |
a
Indicates trend toward statistically significance compared to free docetaxel (P = 0.12).
b
Indicates statistical significance compared to free docetaxel (P = 0.008).
c
Indicates statistical significance compared to saline (P < 0.006).