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. Author manuscript; available in PMC: 2015 Sep 4.
Published in final edited form as: Mol Cell. 2014 Aug 14;55(5):708–722. doi: 10.1016/j.molcel.2014.07.005

Figure 2. NF-Y co-occupies enhancers with ESC-specific master TFs.

Figure 2

(A) Frequency distribution of NF-Y sites within 1 kb of TSSs.

(B) Proximity of NF-Y sites to TSSs.

(C) Levels of DNase I hypersensitivity, H3K4me1, H3K27ac, and H3K4me3 near proximal and distal NF-Y sites.

(D) Hi-C interaction density near proximal and distal NF-Y sites.

(E) TF binding motifs enriched within distal vs proximal NF-Y sites. CTCF is not enriched at either set of NF-Y sites.

(F) Co-occupancy between ESC TFs (Chen et al., 2008; Ho et al., 2011; Ma et al., 2011; Marson et al., 2008) and NF-Y at distal and proximal sites.

(G) Gene ontology categories enriched among distal and proximal NF-Y target genes.