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. Author manuscript; available in PMC: 2014 Sep 8.
Published in final edited form as: Acc Chem Res. 2011 Aug 2;44(10):990–998. doi: 10.1021/ar2000315

FIGURE 4.

FIGURE 4

Confocal laser scanning micrographs of HeLa cells incubated with rapidly degrading hexnut particles (green) and nondegrading hexnut particles (red). Micrographs (A–C) highlight the phases of particle degradation: swelling (a), fragmentation (b), and complete degradation (c). The nondegradable particles showed no change when exposed to intracellular conditions (d). Scale bar represents 10 μm for all images. Reprinted with permission from ref 38. Copyright 2010 American Chemical Society.