Table 2.

Effect of dilution on the weight-average sedimentation coefficient of preformed apoC-II fibrils

Dilution	Detection methoda	Initiallya	After 7 or 14 daysa
Undiluted	OD	98.4	98.2
1:3	OD	86.1	84.2
Undiluted	Fluorescence	96.2	98.5
1:10	Fluorescence	76.3	62.4
1:100	Fluorescence	65.0	65.3

Studies were performed using preformed Alexa488-labeled apoC-II fibrils.

^aWeight-average sedimentation coefficients in Svedberg units (S) were measured using SEDFIT⁴⁴ Results are presented for initial samples and for samples incubated at 25 °C for 7 days for optical density at 280 nm measurements or 14 days for samples monitored by Alexa488 fluorescence.