. 2014 Sep 8;9(9):e106756. doi: 10.1371/journal.pone.0106756

Table 1. The anti-EV71 IgG response after EV71vac immunization.

Group	IgG titer (GMT)^#
	Pre-immune (0 week)	After 1^st vaccination^$ (3 weeks)	After 2^nd vaccination (6 weeks)	After 3^rd vaccination (9 weeks)	12 weeks	26 weeks	39 weeks	56 weeks
High dose	<200	1903±5800	9051±22853	12800±22074^*	15222±9600	800±2696	1131±1238	476±640
Low dose	<200	1600±2693	4525±4800	7611±10245	7611±4800	476±1450	400±690	238±150
PBS	<200	<200	<200	<200	<200	<200	<200	<200

The IgG titer was assayed with plates coated with EV71/E59 (B4 subgenotype) and the geometric mean titer (GMT) ± standard error (SE) was shown.

Three groups were immunized three times with 10 µg (high dose; n = 4) or 5 µg (low dose; n = 4) of EV71vac vaccine or PBS (n = 2) formulated with alum.

*There is a significant difference between high and low dose group (p<0.05, tested by Two-way ANOVA).