Table 1. Correlations of IFN modules with clinical and biological markers of SLE activity.
The levels of IFN modules upregulation (% difference) were correlated with clinical and biological markers of activity in the 157 SLE samples.
| IFN modules | M1.2 | M3.4 | M5.12 | |
|---|---|---|---|---|
| SLEDAI score | ||||
| spearman correlation | 0.05 | 0.12 | 0.21 | |
| p-value | 0.54 | 0.13 | 0.008 | |
| Flare (no flare, mild/moderate flare, or severe flare) | ||||
| spearman correlation | 0.12 | 0.2 | 0.28 | |
| p-value | 0.13 | 0.012 | 0.0003 | |
| Cutaneous flare | ||||
| spearman correlation | 0.11 | 0.15 | 0.21 | |
| p-value | 0.17 | 0.05 | 0.01 | |
| Articular flare | ||||
| spearman correlation | −0.13 | −0.024 | 0.023 | |
| p-value | 0.11 | 0.77 | 0.77 | |
| Hematological flare | ||||
| spearman correlation | −0.012 | −0.043 | 0.055 | |
| p-value | 0.13 | 0.6 | 0.5 | |
| Renal flare | ||||
| spearman correlation | 0.066 | 0.13 | 0.22 | |
| p-value | 0.41 | 0.1 | 0.007 | |
| Anti-dsDNA titer | ||||
| spearman correlation | 0.28 | 0.26 | 0.19 | |
| p-value | 0.0007 | 0.0015 | 0.002 | |
| Low C3 or C4 | ||||
| spearman correlation | 0.072 | 0.086 | 0.12 | |
| p-value | 0.37 | 0.29 | 0.14 | |