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. 2014 Sep 8;9(9):e106942. doi: 10.1371/journal.pone.0106942

Table 3. Summary of abundance changes of proteins involved in purine biosynthesis pathways.

Protein Name Gliotoxin v Control (i) H2O2 v Control (ii) Co-addition v Control (iii) Co-addition v Gliotoxin (iv) Co-addition v H2O2 (v) CADRE ID. (AFUA_) Spot No.
Proteins involved in purine salvage pathway
Adenine phosphoribosyl transferase Apt1 ↑ 20.5* 7G02310 N/A
Xanthine-guanine phosphoribosyl transferase Xpt1 ↑ 3.4* ↑ 1.8 ↑ 1.6 4G04550 992
Proteins involved in de-novo purine biosynthesis
Glutamine amidotransferase: cyclase ↓ 1.9 ↓ 1.7 2G06230 968
Bifunctional purine biosynthesis protein Ade1 ↓ 1.8 6G04730 959

Fold increase (↑) or decrease (↓) of protein, relative to the respective control. CADRE ID., A. fumigatus gene annotation nomenclature according to [1] and [71]; Spot No, according to Figure 2.

*Change in protein abundance was reported previously [20], [23].