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. 2014 Sep 8;9(9):e106915. doi: 10.1371/journal.pone.0106915

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© 2014 S S et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The effect of cell contractility on de-adhesion dynamics was studied for three contractility values: at the cell end, while keeping other parameters fixed. (a) Plot of contractile force at equilibrium for varying stiffness ratios for different contractility values. (b) Influence of cell contractility on de-adhesion dynamics, with other parameters kept constant. On a substrate of given stiffness, higher contractility led to faster de-adhesion.

Inline graphic — The effect of cell contractility on de-adhesion dynamics was studied for three contractility values: at the cell end, while keeping other parameters fixed. (a) Plot of contractile force at equilibrium for varying stiffness ratios for different contractility values. (b) Influence of cell contractility on de-adhesion dynamics, with other parameters kept constant. On a substrate of given stiffness, higher contractility led to faster de-adhesion.